Interesting... NEXTSTEP 3.3 that I have on it doesn't like my formatted in OS/2 FAT-12 (aka "DOS") ED disk. I'll have to try formatting it in MS-DOS to be sure. (Yes, it is a "real" ED MB disk.)

Edit: Your PDF seems to imply that it only supports 1440 and 720 KB DOS and 1.4 MB Mac disks. No 800 or 400 KB Mac, and no 2880 KB DOS.