Except for the occasions when it doesn't work.
The Plus tends to have trouble with drives over about 1GB (it's not the capacity as much as newness). Booting from them is often impossible, for one thing. The timing loops used by the Plus's SCSI implementation (the Plus is unique in its lack of SCSI hardware handshaking) apparently cause this behavior. I wish there were a patch to solve this problem -- it would be great to have a gigundus, bootable drive for my Plus!