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E85 Ethanol can be had for $3.50/gal on average, but only at a limited number of stations. The upside is that it burns cleaner and reduces dependence on foreign oil, while the downside is that it has less MPG than gas. Less enough where I think it's still overall cheaper to buy gas.

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My pickup can run on E85. My experience is about a 4-5 MPG drop when running on E85 which slightly raises my fuel costs at current prices. For a while E85 was cheap enough that I came out slightly ahead, but that was about 2 years ago.

If I happen to stop at a station that has E85 I'll get it, but I don't go out of my way for it.