Have you priced the 53C80 these days? I don't think they're all that readily available.
Then again, if only ten people are ever going to want the solution, I guess it doesn't matter if the chips are $10 each.
However, if someone does decide to program up a new driver solution, that person may wish to consider contacting me. I have a brick of over 500 53C96 SCSI chips and I'd be happy to donate up to 100 of them to such a project. If one went that route the driver guy would want to code for the 53C96 instead of the 53C80. Altering the hardware design would probably be trivial.
In most of the projects the hardware is mostly trivial, though somewhat expensive to design. It's getting the software drivers written and figured out that's tough. We do seem to lack devoted software hobbyists.