Solid lead is not that big of a problem (doctors have been known to leave lead bullits in hard to reach places in people with no ill effects), but lead paint in solvents that will soak into you or lead fumes breathed in are bad.

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course to actually vaporise lead you need heat over 800 degrees F, which in this case will destroy anything around it on a pcb well before hand

The flux smoke is not exactly harmless either since it is a mild acid, but a simple fan takes care of that