Companies have been taking computer motherboards and adapting them to specific uses for a long time. I saw a Tandy Color Computer in a blue case with an Agway label on it once. Apparently, Agway had a service for farmers for looking up weather reports, relevant farming information and placing orders and the Tandy computers were used as terminals to access the service. There was also a company called AllData that made specialized computers for use in the auto repair trade for invoicing and parts cataloging that had Atari ST motherboards inside.

Technically, it doesn't really qualify as a clone since that isn't how it was marketed. Imagine, though, this company bought a Q650 for a few thousand, installed some specialty software on it then turned around and charged $600,000 for it. How many pieces of software would you pay $597,000 for?