I was able to open my HD20SC housing after spending about 1.5 hours on it. I took so much time because I wasn't sure exactly where to apply pressure on the plastic tabs that hold it together. I should have taken photos of the process so others could do the job more easily. Sorry about that. But what I can say is that it can be done. As I recall, I had to use 2 flat-head screw drivers to slowly open the case, bit by bit.
Here are a couple photos of my HD20SC sitting beneath my SE/30:


And here is the SCSI hard drive mechanism I used to swap out the stock drive:
http://www.flickr.com/photos/66071596@N00/527548551/
Lastly, I would like to add that I put a resistor in line with the fan. That reduces it's speed and overall cooling, but once you peer inside the HD20SC housing, you will see that the drive will definitely be cool enough with a lower fan speed (and perhaps even no fan at all). I reduced the fan speed with the resistor in order to reduce the noise. In the stock condition, the fan is louder than even a loud hard drive!