One of the bigger annoyances I have with it is a lack of a way to access physical optical discs. :/ Now when I want to get files off CDs in 64bit win 7 and 64bit vista I use a real Mac to put the files on an image and copy that image to the PC. It may work most of the time but it is far from ideal.
Also HFwhateverExplorer under vista and win 7 seems to trash the resource forks of files if you try to copy from image to image, it works fine in XP however. -_-