I hadn't thought of a breakout box, but I'm thinking that might be overkill since all I need at the moment is ethernet, a few USB, HDMI, and maybe an eSATA. They're all pretty small and might fit in the existing DB25 and DB19 holes. Cost is probably the big thing doing it that way, because panel mount USB 3.0 port extensions are about $5/each, HDMI about $10, eSATA probably around $5, Ethernet $2. Probably an extra $30 for all the ports I'd need. Although it is encouraging that after looking for these things on eBay to see that they actually do exist.