The 400k drive mechanism is the same. You could also use an 800k drive under Macworks with a ROM replacement.
I have Lisas running both LisaOS and Macworks, if you're feeling rowdy on the firmware front
I guess I could try a 400k image on my 400k Macworks machine on the internal floppy cable. Since it uses a Mac drive I don't think it should be a problem, but I don't want to fry my new Floppy Emu