I'd probably leave the SE as is. If necessary, either use a ZFP case for a hard drive, or install an internal. The 800K drive will read/write MFS 400K disks no problem. Set it up with 6.0.8 or a light install of 7.1, and it should work fine.
Re: the 5215CD, I suspect it has the same controller chip as a 7200 or 7500, so it probably will just continually run the eject motor on the auto-inject Sony mechanisms.
-J