If your OS X Mac is not 'always-on' it will pine for its Unix antecedents. That is, it will not do its wee-small-hours housekeeping. MacJanitor is a freeware script to allow you to do the daily, weekly and monthly chores at a time of your choosing.

http://homepage.mac.com/brianhill/macjanitor.html

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(60x) 13DT + 3PB + PTPro; (G3) 7DT/MT; (G4) 3T + PB. System 8.1 to OS 10.5.8