Well the first thing I would do is perform modifications to get that clock speed up to at least 16Mhz. as it sits stock, its slowwwwww.....

If you want more power in a Lisa you would like my MISA or LACINTOSH.

https://68kmla.org/forums/index.php?/topic/25212-is-it-a-lisa-is-it-a-macintosh/

I wonder if I could attach a SE/30 motherboard to it.

yeah I seen it. You can put an se/30 board in there no problem